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To study the efficacy and safety of Rivaroxaban in the prevention of venous thromboembolism after Total Hip and Knee Arthroplasty

December 10, 2017/in Volume 3 | Issue 2 | Sep-Dec

Vol 3 | Issue 2 | Sep-Dec 2017 | page: 3-7 | S. K. Rai, V. P. Raman, Naveen Shejale, S. S. Wani, Rohit Varma Author: S. K. Rai [1], V. P. Raman [2], Naveen Shejale[3], S. S. Wani [1], Rohit Varma [1]. [1]Department of Orthopaedics, Indian Naval Hospital Ship Asvini, Colaba, Mumbai, 400005, India. […]

Acute Complete Acromioclavicular Dislocations: A Prospective Multicenter Therapeutic Study Comparing Combined Intra-articular and Extra-articular Fixation with Intra-articular K-wire Fixation

December 10, 2017/in Volume 3 | Issue 2 | Sep-Dec

Vol 3 | Issue 2 | Sep – Dec 2017 | page: 21-24 | Biswajit Sahu, Ranajit Panigrahi, Nishit Palo, Ashok Priyadarshi, Saswat Samant Author: Biswajit Sahu [1], Ranajit Panigrahi [2], Nishit Palo [3], Ashok Priyadarshi [4], Saswat Samant [5]. [1] Department of Orthopaedics, VSS Medical College. [2] Department of orthopedics, Hi-Tech Medical College [3] Department […]

To study the efficacy and safety of Rivaroxaban in the prevention of venous thromboembolism after Total Hip and Knee Arthroplasty

December 10, 2017/in Volume 3 | Issue 2 | Sep-Dec

Acute Complete Acromioclavicular Dislocations: A Prospective Multicenter Therapeutic Study Comparing Combined Intra-articular and Extra-articular Fixation with Intra-articular K-wire Fixation

December 10, 2017/in Volume 3 | Issue 2 | Sep-Dec

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To study the efficacy and safety of Rivaroxaban in the prevention of venous thromboembolism after Total Hip and Knee Arthroplasty

December 10, 2017/in Volume 3 | Issue 2 | Sep-Dec

Vol 3 | Issue 2 | Sep-Dec 2017 | page: 3-7 | S. K. Rai, V. P. Raman, Naveen Shejale, S. S. Wani, Rohit Varma

Author: S. K. Rai [1], V. P. Raman [2], Naveen Shejale[3], S. S. Wani [1], Rohit Varma [1].

[1]Department of Orthopaedics, Indian Naval Hospital Ship Asvini, Colaba, Mumbai, 400005, India.
[2]Malla Reddy Institute of Medical Sciences, Suraram, Hyderabad, 500055, India.
[3]Department of Orthopaedics, Indian Naval Hospital Ship Kalyani, Visakhapatnam, 530005, India.

Address of Correspondence
Dr. SK Rai
Department of Orthopaedics, Indian Naval Hospital Ship Asvini, Colaba, Mumbai, 400005, India.
Email: skrai47@yahoo.com

Learning Points for this Article: To prevent of venous thromboembolism after total Hip and Knee Arthroplasty there is parenteral low molecular weight heparin is available and being used in many centers but it has to be given my trained paramedic or nurse however oral drug like Rivaroxaban in once daily doses and it is patients friendly and can be taken at home after discharge. It is safe and as effective as parenteral low molecular weight heparin.

Abstract

Objective: Development of venous thrombo-embolism (VTE) including deep venous thrombosis (DVT) is a common complication after total hip and total knee Arthroplasty, pelvic fracture or long bone fractures especially in the lower limb. Currently used drugs for DVT prophylaxis after these procedures have important limitations, including parenteral administration, and unpredictable plasma levels requiring frequent monitoring and dose adjustment leading to decreased patient compliance. In our study we used oral rivaroxaban, which is one of the newer oral anticoagulants and is a direct factor Xa inhibitor that has demonstrated superior efficacy, compared to that of enoxaparin or any parenteral low molecular weight heparin (LMWH).
Materials and Methods: In our study, 180 patients who underwent Total knee replacement (TKR) or Total hip replacement (THR) in our center were included. They were put on oral rivaroxaban, 10 mg once daily, started 6 h after surgery and continued for 3 weeks in case of TKR and 6 weeks in case of THR.
Results: VTE and DVT are common complications after THR and TKR and cause a substantial burden to patients, healthcare providers, increase costs to the patients and increase both morbidity and mortality, if not addressed promptly. Currently available anticoagulants in the form of subcutaneous injection have limitations that lead to decreased compliance with DVT prophylaxis guidelines. Rivaroxaban which is oral 10 mg once daily has superior efficacy compared to enoxaparin or any parenteral LMWH for the prevention of the same and the patient compliance is also very good. There were no incidences of increased bleeding or wound infection in our study as compared to control group which were given subcutaneous enoxaparin.
Keywords: Venous thrombo-embolism, deep vein thrombosis, Total knee replacement, Total hip replacement, Rivaroxaban, deep venous thrombosis prophylaxis.

References

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How to Cite this article: Rai S K, Raman V P, Shejale N, Wani S S, Varma R. To study the efficacy and safety of Rivaroxaban in the prevention of venous thromboembolism after Total Hip and Knee Arthroplasty. Trauma International Sep – Dec 2017;3(2):3-7.

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Acute Complete Acromioclavicular Dislocations: A Prospective Multicenter Therapeutic Study Comparing Combined Intra-articular and Extra-articular Fixation with Intra-articular K-wire Fixation

December 10, 2017/in Volume 3 | Issue 2 | Sep-Dec

Vol 3 | Issue 2 | Sep – Dec 2017 | page: 21-24 | Biswajit Sahu, Ranajit Panigrahi, Nishit Palo, Ashok Priyadarshi, Saswat Samant

Author: Biswajit Sahu [1], Ranajit Panigrahi [2], Nishit Palo [3], Ashok Priyadarshi [4], Saswat Samant [5].

[1] Department of Orthopaedics, VSS Medical College.
[2] Department of orthopedics, Hi-Tech Medical College
[3] Department of Orthopaedics, Santosh Medical College,Ghaziabad, UP.
[4] Department of orthopedics, Hi-Tech Medical College, Bhubaneswar

Address of Correspondence
Dr Saswat Samant
Department of Orthopaedics, Hi-tech Medical College
Bhubaneswar.
Email: Saswatsamant135@gmail.com

Learning Points for this Article: Isolated intra-articular K-wire fixation also fails to provide the required stability to the injured joint, especially in developing countries, where patients fail to adhere to the rehabilitation protocol. Thus, combining both, the intra-articular and coracoclavicular fixations seem to be a promising modality in terms of stability and secure fixation. Combining the intra- and extra-articular techniques significantly decreases the complication rates as seen with the isolated fixation techniques.

Abstract

The AC joint is commonly involved in traumatic injuries that affect the shoulder.Treatment of these injuries has been controversial and continues to evolve to this day ranging from conservative management and k-wire fixations to screw fixation, and more recently, arthroscopically assisted ligament reconstructions with no definite consensus about the ideal method of treatment.Each modality has its own advantages and disadvantages. In this prospective therapeutic multicenter study, we compared combined intra-articular fixation and screw coracoclavicular repair versus the intra-articular fixation with k-wires alone to assess the stability, failure rates, and outcomes of combining the two methods of fixation versus isolated intra-articular fixation.combining both, the intra-articular and coracoclavicular fixations seem to be a promising modality in terms of stability and secure fixation. Combining the intra- and extra-articular techniques significantly decreases the complication rates as seen with the isolated fixation techniques.
Keywords: Acromioclavicular dislocations, intra-articular, multicenter.

References

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How to Cite this article: Sahu B, Panigrahi R, Palo N, Priyadarshi A, Samant S. Acute Complete Acromioclavicular Dislocations: A Prospective Multicenter Therapeutic Study Comparing Combined Intra-articular and Extra-articular Fixation With Intra-articular K-wire FixationTrauma International Sep-Dec 2017;3(2):21-24.

Half Sized Blog Element (Single Author Style)

Half Sized Blog Element (Multi Author Style)

To study the efficacy and safety of Rivaroxaban in the prevention of venous thromboembolism after Total Hip and Knee Arthroplasty

Acute Complete Acromioclavicular Dislocations: A Prospective Multicenter Therapeutic Study Comparing Combined Intra-articular and Extra-articular Fixation with Intra-articular K-wire Fixation

To study the efficacy and safety of Rivaroxaban in the prevention of venous thromboembolism after Total Hip and Knee Arthroplasty

Acute Complete Acromioclavicular Dislocations: A Prospective Multicenter Therapeutic Study Comparing Combined Intra-articular and Extra-articular Fixation with Intra-articular K-wire Fixation

Full Sized Blog Element (Big Preview Pic)

To study the efficacy and safety of Rivaroxaban in the prevention of venous thromboembolism after Total Hip and Knee Arthroplasty

Author: S. K. Rai [1], V. P. Raman [2], Naveen Shejale[3], S. S. Wani [1], Rohit Varma [1].

Abstract

References

(Abstract) (Full Text HTML) (Download PDF)

Acute Complete Acromioclavicular Dislocations: A Prospective Multicenter Therapeutic Study Comparing Combined Intra-articular and Extra-articular Fixation with Intra-articular K-wire Fixation

Author: Biswajit Sahu [1], Ranajit Panigrahi [2], Nishit Palo [3], Ashok Priyadarshi [4], Saswat Samant [5].

Abstract

References

(Abstract) (Full Text HTML) (Download PDF)

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